Diagnostic value of FibroTouch controlled attenuation parameters for hepatic steatosis in NAFLD patients

Objective To evaluate the diagnostic value of FibroTouch controlled attenuation parameters for hepatic steatosis with MRI IDEAL-IQ sequence as the criterion. Methods The subjects receiving physical examination were recruited in this study. Regarding MRI IDEAL-IQ sequence as the assessment criterion, the diagnostic value and the accuracy of quantitative analysis of FibroTouch controlled attenuation parameters for moderate and severe hepatic steatosis were analyzed. Results A total of 104 subjects were recruited with a male-to-female ratio was 2.47∶1, aged （41.6±12.2） years on average, and the fat attenuation parameter was （288.2±5.1） dB/m. The number of patients diagnosed with fatty liver, moderate or severe fatty liver and severe fatty liver by FibroTouch was 82, 66 and 50, respectively. The diagnostic rates were calculated as 78.8%, 63.5%and 48.1%, respectively. The number of patients diagnosed with fatty liver, moderate or severe fatty liver and severe fatty liver by MRI IDEAL-IQ was 82, 51 and 11, respectively. The diagnostic rates were 78.8%, 49.0% and 10.6%, respectively. Compared with the ROC curve of MRI IDEAL-IQ,the areas under the curve of ROC were 0.956,0.956 and 0.839（all P < 0.01）, respectively. The cut-off values were 264.5, 300.2 and 327.0, respectively. Conclusions FibroTouch controlled attenuationparamaters have similar diagnostic value in terms of qualitative and quantitative diagnosis of fatty liver with MRI IDEAL-IQ. FibroTouch is an economical and reproducible noninvasive examination method, which may become the optimal option after the screening and treatment of fatty liver.