Abstract: Objective To explore the challenges faced by individuals with visual impairment and autism, and analyze possible supporting measures and solutions. Methods A qualitative research was adopted by conducting interviews through voice and text-based communication methods among autism individuals with a history of visual impairment who were enrolled via recommendation and online networking by purposive sampling method. The difficulties and potential solution of visually impaired individuals with autism were collected. The interview content was designed mainly based upon common contents during previous interaction with the participants. Results Challenges included accessibility to healthcare services, the challenging situation arising from the comorbidity of visual impairment and autism, stereotype, the incompatibility of traditional vocational training for autistic individuals with visual impairment, unfriendly social environment and mental health issues, etc. Conclusions The visually impaired population with autism exists but receives insufficient attention. It is necessary to strengthen early screening and intervention, enhance the education of relevant knowledge for professionals, broaden major options in universities and make concrete efforts, thereby creating a better future for visually impaired individuals with autism.