机器人辅助腹腔镜与传统腹腔镜方式治疗输尿管梗阻的meta分析

Meta-analysis of robot-assisted laparoscopy versus traditional laparoscopy in the treatment of ureteral obstruction

  • 摘要: 目的通过meta分析比较机器人辅助腹腔镜手术与传统腹腔镜手术方式治疗输尿管梗阻的疗效。方法通过检索中国知网、万方数据知识服务平台、维普网、中国生物医学文献数据库、PubMed、Embase、Cochrane Library、Web of Science数据库,检索时限为建库至2024年8月8日。中文检索词包括“输尿管”“梗阻”“机器人辅助手术”“机器人外科手术”,英文检索词包括“Ureter”“Obstruction”“Robot Assisted Surgery”“Robotic Surgical Procedure”。比较2种手术方式的术中出血量等指标差异。结果共纳入30项研究2 314例患者。Meta分析结果显示,机器人组术中出血量WMD(95%CI)=-5.44(-10.64,-0.24)mL,P = 0.040、手术时间WMD(95%CI)=-16.47(-27.49, -5.44)min,P = 0.003、住院时间WMD(95%CI)=-0.55(-0.65,-0.45) d,P < 0.001、引流管留置时间WMD(95%CI)=-1.04(-1.67,-0.41) d,P = 0.001、术中吻合时间WMD(95%CI)=-11.26(-21.98,-0.54)min,P =0.040、术中缝合时间WMD(95%CI)=-19.72(-33.76,-5.67)min,P = 0.006少于传统腹腔镜组,成功率OR(95%CI)=2.42(1.36,4.32),P = 0.003和住院费用WMD(95%CI)=33 756.24(25 689.01,41 823.47)元, P < 0.001高于传统腹腔镜组。2组并发症发生率OR(95%CI)=0.79(0.57,1.09),P = 0.144、二次手术率OR(95%CI)=1.13(0.50,2.55),P = 0.762、输尿管支架留置时间WMD(95%CI)=0.00(-1.12,1.13)d,P = 0.994差异无统计学意义。结论机器人辅助腹腔镜手术可以减少术中出血量,缩短术中操作时间、住院时间、引流管留置时间、术中吻合时间和缝合时间,提高成功率,适合用于高难度、高要求的精细手术,临床应用价值较高,但其费用较高。

     

    Abstract: ObjectiveTo compare the efficacy of robot-assisted laparoscopic surgery and traditional laparoscopic surgery in the treatment of ureteral obstruction through a meta-analysis. MethodsA comprehensive literature search was conducted in CNKI, Wanfang Data, VIP, CBM, PubMed, Embase, Cochrane Library, and Web of Science, covering publications from inception to August 8, 2024. The Chinese and English search terms included “Ureter” “Obstruction” “Robot-Assisted Surgery” and “Robotic Surgical Procedure”. Intraoperative blood loss and other surgical outcomes were compared between the two approaches. ResultsA total of 30 studies involving 2 314 patients were included. The results of meta-analysis showed that the robotic group had significantly reduced intraoperative blood loss WMD(95%CI)= -5.44 (-10.64, -0.24) mL, P = 0.040, shorter operative time WMD = -16.47 (-27.49, -5.44) min, P = 0.003, reduced length of hospital stay WMD =-0.55 (-0.65, -0.45) d, P < 0.001, shorter duration of drainage tube placement WMD = -1.04 (-1.67, -0.41) d, P = 0.001, decreased anastomosis time WMD = -11.26 (-21.98, -0.54) min, P = 0.040, and shorter suture time WMD = -19.72 (-33.76, -5.67) min, P = 0.006 compared with the traditional laparoscopic group. The robotic group also demonstrated a higher surgical success rate OR = 2.42 (1.36, 4.32), P = 0.003 and higher hospitalization costs WMD = 33,756.24 (25,689.01, 41,823.47) RMB, P < 0.001. No significant differences were observed in complication rate OR (95%CI) =0.79 (0.57, 1.09),P = 0.144, reoperation rate OR (95%CI)=1.13(0.50, 2.55), P = 0.762, or ureteral stent retention time WMD(95%CI)= 0.00(-1.12,1.13) d, P = 0.994 between the two groups. ConclusionRobotic-assisted laparoscopic surgery has been shown to significantly reduce intraoperative blood loss, shorten operative time, hospital stay, drainage duration, anastomosis time, and suturing time, while improving surgical success rates. It is particularly suitable for complex and technically demanding procedures that require precision, offering substantial clinical value despite its relatively high cost.

     

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