Abstract: Objective To evaluate the clinical efficacy of arthroscopic rotator cuff repair combined with modified inter tubercular groove tenodesis in the treatment of long head of biceps brachii tendon （LHBT） injury complicated with rotator cuff injury. Methods Thirty-one LHBT patients complicated with rotator cuff injury were recruited in this study. The visual analogue scale（VAS） score, Constant-Murley shoulder outcome score and American Shoulder and Elbow Surgeons （ASES） score were recorded before and 18 months after treatment. The shoulder active range of motion（ROM） and the morphological changes of the upper arm were observed. Results All 31 LHBT patients successfully completed the surgery. Compared with preoperative data, the VAS score was significantly lower, the Constant-Murley shoulder outcome score and ASES score were significantly higher and the shoulder active ROM （forwarding flexion, abduction, 90° abduction external rotation and 90° abduction internal rotation） was remarkably improved （all P < 0.05）. Postoperative complications occurred in 3 patients （10%） including 2 cases of shoulder joint adhesion and 1 case of Popeye deformity. Neither infection nor rotator cuff tearing occurred. Conclusion Arthroscopic rotator cuff repair combined with modified intertubercular groove tenodesisis an efficacious treatment of LHBT injury complicated with rotator cuff injury.