Abstract: Objective To investigate the correlation between high-density lipoprotein-cholesterol （HDL-C）, low-density lipoprotein-cholesterol （LDL-C）, triglyceride, apolipoprotein A （APOA） and APOB, and cardiovascular events and all-cause death in patients with different stages of chronic kidney diseases （CKD）. Methods Baseline data of all enrolled CKD patients were collected. Clinical prognosis （cardiovascular events and all-cause death） was evaluated during follow-up. The correlation between HDL-C, LDL-C, triglyceride, APOA and APOB, and cardiovascular events and all-cause death was analyzed by Cox’s regression analysis. Results After the adjustment of age, gender, body mass index （BMI）, diabetes mellitus, smoking, alcohol drinking, serum uric acid, serum prealbumin, serum potassium and hemoglobin, LDL-C was the risk factor of cardiovascular events in patients with stage Ⅰ,Ⅱ,Ⅳ,Ⅴ CKD （all P < 0.05）, triglyceride and APOB were the risk factors of cardiovascular events （all P < 0.001）, whereas HDL-C and APOA were not the risk factors of cardiovascular events （all P > 0.05）. HDL-C was the risk factor of all-cause death in patients with stage Ⅰ-Ⅳ CKD （all P < 0.05）. Trigleceride was the risk factor of all-cause death in patients with stage Ⅰ-Ⅲ CKD （all P < 0.001）. APOB was the risk factor of all-cause death in patients with stage I CKD （P = 0.015）. However, LDL-C and APOA were not the risk factors of all-cause death in patients with stage I-V CKD （all P > 0.05）. Conclusions Trigleceride and APOB and TG may play an important role in predicting the prognosis of cardiovascular events and all-cause death in patients with different stages of CKD, which should be highly stressed. HDL-C is of certain significance in predicting all-cause death, whereas LDL-C plays a certain role in predicting the risk of all-cause death. APOA is not involved with the prediction of cardiovascular events and all-cause death.