Abstract: Objective To evaluate the effect of compound Danshen dripping pills on cardiovascular events in patients with acute myocardial infarction （AMI） after coronary stent implantation. Methods A total of 370 AMI patients undergoing coronary stent implantation were recruited and evenly divided into the study and control groups using prospective non-blind method. After admission, patients in two groups received standardized drug therapy for secondary prevention of coronary heart diseases. Patients in the study group were supplemented with compound Danshen dripping pills （10 pills/time, 3 times/d for 6 months）, and those in the control group were not given with compound Danshen dripping pills. Six months later, the incidence of angina, myocardial infarction, cardiac insufficiency, new coronary lesions and total cardiovascular events was assessed in two groups. Results After 6 months, the incidence of angina pectoris （10.00% vs. 17.72%）, myocardial infarction （2.78% vs. 7.78%）, cardiac insufficiency （3.89% vs. 9.44%）, and new coronary lesions （7.78% vs. 14.44%）in the study group was significantly higher than those in the control group （all P < 0.05）. The incidence of total cardiovascular events in the study group was 24.44%, significantly lower compared with 48.33% in the control group （P < 0.05）. Conclusion Compound Danshen dripping pills can reduce the incidence of angina, myocardial infarction, cardiac insufficiency, new coronary lesions, total cardiovascular events in AMI patients after coronary stent implantation.