MRI诊断代谢相关脂肪性肝病的研究进展

Research progress on MRI in diagnosis of metabolic-associated fatty liver disease

  • 摘要: 代谢相关脂肪性肝病(MAFLD)已成为世界范围内慢性肝病的主要病因之一,准确区分单纯脂肪肝、脂肪性肝炎以及MAFLD相关的肝硬化至关重要。由于肝活组织检查的有创性及存在采样误差,无创诊断技术是理想的替代选择。该文对近年来MRI在MAFLD脂肪变性、炎症及纤维化的最新研究进展进行综述,以期为临床无创诊断MAFLD提供依据。

     

    Abstract: Metabolic-associated fatty liver disease(MAFLD) has become one of the major causes of chronic liver disease worldwide. It is crucial to accurately differentiate non-alcoholic fatty liver, steatohepatitis and MAFLD-associated liver cirrhosis. Due to the invasiveness and sampling error of liver biopsy, non-invasive diagnostic method of MAFLD is an ideal alternative. In this article, research progress on the application of magnetic resonance imaging (MRI) in the assessment of hepatic steatosis, inflammation and fibrosis in MAFLD patients were reviewed, aiming to provide evidences for non-invasive diagnosis of MAFLD in clinical practice.

     

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