Abstract: Pancreatic cancer is a highly malignant tumor of the digestive tract, and its precision diagnosis and treatment is a major challenge in clinical practice. With the development of science and technology, artificial intelligence has been applied in the early diagnosis, treatment and prognosis prediction of some diseases, which has high clinical value. Medical imaging is a disciplie to evaluate human health, which consists of two relatively independent directions of medical imaging system and medical image processing. Artificial intelligence based on medical imaging plays an important role in the clinical diagnosis and treatment of pancreatic cancer. In this article, research progress in the application of artificial intelligence in precision diagnosis and treatment of pancreatic cancer was reviewed from the aspects of imaging diagnosis, efficacy evaluation, survival prediction and radiogenomics, etc.