Abstract:
This paper reviews the role of innate lymphoid cells (ILC2s) in the pathogenesis of bronchial asthma and explores the evidence for acupuncture’s regulatory effects on ILC2s in asthma treatment. Preliminary findings suggest that acupuncture may mitigate airway inflammation, curb airway hyperresponsiveness, and enhance airway remodeling in asthma patients by modulating ILC2 secretion and migration. Despite these insights, several challenges remain, including the unclear pathways through which ILC2s are regulated by acupuncture in asthma, a scarcity of animal experiments and clinical studies, and a lack of understanding regarding how acupuncture might improve the mechanisms underlying hormone-resistant asthma via the ILC2 pathway.