Abstract: Objective Discuss the security ,efficacy and advantage of laparoscopy in radical hysterectomy and pelvic lymphadeneetomy in patients with malignant uterine tumors in early stage. Methods The retrospecitive study is involving 127 patients with malignant uterine tumors operated by radical hysterectomy and pelvic lymphadeneetomy from January 1,2007 to November 30,2008 in the department of gynecology, the first affiliated hospital of Sun Yat-sen university, including 92 cervical cancers and 35 endometrial cancers. According to the surgical manner, the patients are divided to two groups: ①49 patients were treated by laparoscopy (laparoscopy group); ②78 patients were treated by laparotomy(laparotomy group). Multiple clinical parameters, including operative duration, blood loss, blood transfusion volume and ratio, the number of removed lymph nodes, pelvic drainage,gastrointestinal function recovery, return to normal temperature, period of using antibiotics, catheter removal time, hospitalization expenditure, WBC count, post-operative complications and recrudescence in the near future were observed and analyzed statistically. Results Compared with the patients in laparotomy group，the patients in laparoscopy group had a longer operative duration(275.5±47.4)min vs (247.9±41.7)min, less blood loss(230.2±166.9)ml vs (448.1±268.2)ml, less blood transfusion(475.0±221.7)ml vs (714.3±290.5)ml，less pelvic drainage(169.2±168.1)ml vs (522.3±626.7)ml, shorter internal of postoperative gastrointestinal function recovery (2.3±0.7)d vs (2.7±0.8)d. Conclusion Laparoscopy in radical hysterectomy and pelvic lymphadeneetomy is safe for patients with malignant uterine tumors in early stage. Compared with laparoectomy, laparoscopy has the the advantages of minimal invasion and fast recovery.