Abstract: Objective To explore the diagnosis value of fujinon intelligent chromoendoscopy(FICE) in early gastric tumor． Methods Eeight thousand two hundred and thirty-one patients who had gastroscopy examination were divided into two groups randomly. Group A had 4 356 patients. Group B had 3 875 patients .The patients were chosen by gastric mucosa lesion (consist of gastric ulcer, gastric tumor or polypus). Group A was applied FICE technique and Group B was applied magnifying chromoendoscopy technique to observe the pattern of gastric pits and mucosa micrangium. To diagnosis gastric mucosa lesion and compare them with histopathology diagnosis，then to analyze the relation of them．Results Group A 189 patients had 203 focus including 21 atypical hyperplasia focus and 16 gastric tumors. Group B 133 patients had 141 focus including 14 atypical hyperplasia focus and 10 gastric tumors. Both of the FICE technique and magnifying chromoendoscopy technique could clear display the pattern of gastric pits and mucosa micrangium. But FICE technique could significant display the pattern of mucosa micrangium than magnifying chromoendoscopy technique. Conclusions The FICE technique has high coincidence rate of diagnose and significant display the pattern of mucosa micrangium. It is easy to apply FICE to observe gastric pits and mucosa micrangium in gastric mucosa lesion beneficial to target biopsy. It has good clinical practical value．