Abstract: Objective To investigate the schizophrenia cognitive function defect.Methods:64 cases of schizophrenia patients and 53 normal control group were tested by Stroop test, Digit Symbol-Coding, WAIS- Ⅲ symbol search, Set the pace of continuous adding test, Wisconsin Card Sorting Test (WCST-64) .The results were examined by SPSS16.0 t test analysis.Results Compared to normal controls, patients have statistically significant differences in Stroop word,Stroop color,Stroop color word, Digit Symbol Coding, WAIS-Ⅲ symbol search score, pace the continuous adding test attempts, pace the continuous adding test correct number, the Wisconsin Card Sorting Test number (WCST), WCST correct number, WCST continued correct numbers,WCST random error number,WCST completed the classification number.Conclusion Patients with schizophrenia have impairment in cognitive function in attention, memory, executive function, information processing, abstraction ability, concept formation and other aspects.