Abstract: Diabetes mellitus,one non-infectious disease(NCD),is currently considered as one main killer to human health by the international community . Dtection of glycaemia is particularly important to diabetic diagnosis and treatment, and prevention of its acute and chronic complications. HbA1c can reflect the level of glycaemia during the past 2-3 months. And it has been recommended as a diagnostic test of diabetes mellitus at present. Now is summarized the research progress of HbA1c in this paper.