Abstract: Metabolic syndrome is a set of clinical syndromes with dyslipidemia, hypertension, abdominal obesity and insulin resistance as the main manifestations, and is a risk factor for diabetes mellitus and cardiovascular diseases. In recent years, more and more researches on metabolic syndrome and skin diseases have been conducted. In this article, the research progress on metabolic syndrome in the pathogenesis of related skin diseases including psoriasis, acne, hidradenitis suppurativa, acanthosis nigricans, lichen planus and androgenetic alopecia was elucidated, aiming to provide new ideas for the prevention and treatment of metabolic syndrome and related skin diseases.